Promethazine

Laboratory Report # 3.2 Title:         promethazine 0.2% Syrup          Date:                   disciple Name: 1.         Describe the dispensing directions for the grooming:         A. Indication and expected deed:                           Promethazine HCL is a right antihistamine drug hired to plow allergic conditions and,                  beca engross of the sedative action, insomnia. It is in any case used as an anti-tussive in cough mixings.         Promethazine substructure be administered by verbalise or injection.         B. Directions/administration/use: Sig:         TAKE ONE teaspoon OF SYRUP BY verbalise AT MEALTIMES AND AT BEDTIME.         C. Precautions/DI: turn over medication out of r distributively of children Do non booze alcohol while on this medication Contraindications: ·         children under 2yrs ·         SC or intra-arterial injection ·         narrow-angle glaucoma ·          prostatic hypertrophy ·         bladder or pyeloduodenal obstruction ·         MAOI therapy ·         hypersensitivity to promethazine and other phenothiazines Adverse Reactions: somnolence dizziness ·         xerostomia ·         extrapyramidal reactions                  do drugs Interactions: belladonna benztropine cabergoline cisapride dofetilide gatifloxacin grepafloxacin halofantrine levofloxacin lithium meperidine hydrochloride hydrochloride moxifloxacin orphenadrine pimozide porfimer procyclidine sotalol sparfloxacin tramadol trihexyphenidyl          D. retentivity: Keep the syrup at room temperature, away from heat, light, and moisture. Do not freeze.         E. Missed panelling: Use your medicine as soon as you urge that you have mixed-up your dose. If it is about time for your next dose, break back until thence to use the medicine and skip the missed dose. You should not use both doses at one time. 2.          design of each excipient used in the experiment: burnt umber         -          flavourer mover Sucrose         -          lure agent, suspending and viscosity-increasing agent. Liquid Glucose         -         to provide calories, taste, and to modify cristal of atomic calculate 11                                    and urine crossways the intestinal barrier by osmosis          glycerine         -         used as a demulcent in cough preparations for soothing and defend                           the mucous membranes and relieves irritation. When administered by                            mouth or parenterally, glycerin increases the blood plasma osmolality,                           resulting in the movement of water supply by osmosis from the extra vascular                           spaces into the plasma. atomic number 11 Chloride-         electrolyte - source of atomic number 11 (Na+), used in crew with glucose for oral rehydration in piercing diarrhea. Vanillin         -         flavoring/perfuming agent Sodium Benzoate         preservative with antibacterial and anti-fungal properties complete(a) pissing         -         diluent 3.         Show your calculations and combine (in steps):         Calculations: Promethazine HCL         2 g                  x         (90mL / one C0mL)         =         0.18 g Cocoa         180 g         x         (90mL / one C0mL)         =         16.

2 g Sucrose         600 g         x         (90mL / 1000mL)         =         54 g Liquid Glucose         180 g         x         (90mL / 1000mL)         =         16.2 g Glycerin         50 mL         x         (90mL / 1000mL)         =         4.5 mL x (1.25g/mL) = 5.625 g Sodium Chloride         2.0 g         x         (90mL / 1000mL)         =         0.18g sp. gravity Vanillin         0.2 g         x         (90mL / 1000mL)         =         0.018 g Sodium Benzoate         1.0 g         x         (90mL / 1000mL)         =         0.09 g P. piddle         1000 mL         x         (90mL / 1000mL)         =         90 mL Ft. 90 mL         Promethazine:         (2 g / 1000 mL)         x 100 % = 0.2% syrup         1 Tsp = 5 mL x (0.2 % / 100 %) = 0.01 g x (1000 mg / 1 g) = 10 mg / dose Preparation: The sucrose and cocoa were merge unneurotic in a beaker. To this smorgasbord, the glucose, glycerin and vanillin were gradually added. The sodium benzoate and sodium chloride were then dissolved in a undersize tot up (30 mL) of hot water. The promethazine HCL was then added to the solution and was complex well. The content were then transferred to the mixture in the beaker. The entire mixture was brought to a boil and the boiling temperature was kept up(p) for 2 minutes. The mixture was allowed to chill out to room temperature and the volume was brought up to 90 mL by adding additional pure water. If you exigency to get a undecomposed essay, order it on our website: Orderessay

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