Preparation of Aspirin (Acetylsalicylic Acid)
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Course: march on General Chemistry (CHEM111)
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Lab construe: November 1, 2010
Submission Date: November 29, 2010
ABSTRACT:
In this experiment, the desired yield was acetylsalicylic virulent, or as it is more(prenominal) commonly known, aspirin. Aspirin is synthesized by the acid-catalyzed reaction of salicylic acid and acetic anhydride. In this experiment, sulfuric acid (H2SO4) was use as the catalyst that was used to speed up the reaction and act as a buffer for the blistering acid. Aspirin has been a household name for everyplace degree Celsius years. Its a popular cure-all and even more uses are being specialised to this day. Since first hitting the market, over a trillion aspirin tablets have been used in the fight against aches and pains [1]. To produce this wonder drug, we reacted salicylic acid with acetic anhydride, which resulted in the desired acetylsalicylic acid and acetic acid. The product was go down through a series of tests, including newly learned 1H-NMR and FTIR tests, to determine the purity and effectiveness of the experiment. After the results were calculated, the experiment appeared successfulâ"producing a near-perfect percentage yield, fair melting point, and good spectroscopy results.
incoming:
Aspirin, or acetylsalicylic acid, is an acetyl derivative of salicylic acid that is a efficacious analgesic (pain reliever), anti-pyretic (reduces fever), anti-inflammatory (reduces swelling), and anti-platelet (slows blood-clotting), non-narcotic drug [3]. It is most commonly used domestically to alleviate headaches and other aches and pains. Aspirin is categorized as a non-steroidal anti-inflammatory drug (NSAID)â"drugs that block the enzyme that makes prostaglandinsâ"which reduces the function of platelets and the dexterity of blood to clot [1].
The history of aspirin can be traced back to the days of Hippocrates, the father of modern medicine. Between the quantify of...
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